The study included 16 participants, all of whom had metabolic syndrome, marked by at least three risk factors that increased their risk for heart disease or diabetes. All participants were fed the same diet, which was altered every three weeks for a total duration of 18 weeks as levels of carbohydrates were progressively increased and saturated fats were decreased. All started with a baseline “low-carb” diet, with the highest carb level reaching over 55% of the daily nutrient intake.
By the end of the trial, participants had lost an average 22 pounds, and experienced significant improvements in blood sugar, insulin levels, and blood pressure. Throughout the study, participants’ blood levels of total saturated fats remained relatively stable and even fell in some when the baseline fat consumption was doubled.